K2X Active Portfolio

Updated October 21, 2024

Consisting of 85+ companies in tech and life science, our investment portfolio is filled with some of the brightest and most promising startups from the US, Canada, Israel, and India.
ACQUIRED BY PRIVATE DANISH COMPANY
AbFero Pharmaceuticals Inc.

AbFero Pharmaceuticals Inc.

Boston, MA

abferopharmaceuticals.com

Dedicated to treating diseases of iron overload

Thomas NeenanCEO

Achelios Therapeutics, Inc.

Achelios Therapeutics, Inc.

Chapel Hill, NC

http://achelios.com

Trans-dermal delivery of drugs for TMJ

Crist Frangakis, PhDCEO

Altis Biosystems

Altis Biosystems

Chapel Hill, NC

https://altisbiosystems.com

Stem cell technology that recreates the human intestinal epithelium

Ben Scruggs, PhDCEO

AmplifiDX

AmplifiDX

Newark, CA

www.amplifidx.com

Next-gen molecular point-of-care disease testing platform

Nancy SchoenbrunnerCEO

AOA Inc.

AOA Inc.

Boston, MA

www.aoadx.com

Extremely sensitive liquid biopsy detection method for ovarian cancer

Oriana Papin-ZoghbiCEO

Astrocyte Pharmaceuticals Inc.

Astrocyte Pharmaceuticals Inc.

Cambridge, MA

www.astrocytepharma.com

Neuroprotection therapies for TBI, concussions, & stroke

William S. Korinek, PhDCEO

Avisi Technologies Inc.

Avisi Technologies Inc.

Philadelphia, PA

www.avisitech.com

Next-gen aqueous shunt to treat glaucoma

Rui Jing JiangCEO

ACQUIRED BY ZOETIS
Basepaws, Inc.

Basepaws, Inc.

El Segundo, CA

www.basepaws.com

First consumer cat DNA kits and study of nutrition relation with DNA

Anna SkayaCEO

Beam Semiconductor

Beam Semiconductor

Rehovot, Israel

beamshaping.io

Compact 5G 60 GHz radio for wireless backhaul

Stacy JosephCEO

BendaRx Corp

BendaRx Corp

Montreal, Canada

Gentler chemotherapeutics targeting blood cancers

Martin NoelCEO

Boardwalktech, Inc.

Boardwalktech, Inc.

Cupertino, CA

www.boardwalktech.com

Patented digital ledger for collaborative enterprise applications

Andrew DuncanCEO

Cardiokol

Cardiokol

Airport City, Israel

www.cardiokol.com

Voice-based markers and methods for monitoring and screening heart rhythm disorders

James AmihoodCEO

Celero Systems, Inc

Celero Systems, Inc

Lincoln, MA

www.celerosystems.com

Ingestible “smart pill” system to detect and reverse opioid overdose

Ben PlessCEO

Chakra Growth Capital

Chakra Growth Capital

Saratoga, CA

www.chakragrowthcapital.com

Fund focused on Indian startups in automation and decarbonizing traditional markets

Sri PurisaiManaging Director

CNote Group, Inc.

CNote Group, Inc.

Oakland, CA

www.mycnote.com

Alternative products offering higher returns for savers

Catherine BermanCEO

CoLabs, Inc.

CoLabs, Inc.

Morgan Hill, CA

www.colabsmedical.com

Device to improve oxygen flow for heart attack victims

Clay NolanCEO

CorInnova, Inc.

CorInnova, Inc.

Houston, TX

www.corinnova.com

Minimally invasive non-blood contacting cardiac device to treat acute heart failure

William AltmanCEO

CorIT Medical

CorIT Medical

Arlington, VA

coritmedical.com

Single use surgical device for the reduction of inferior turbinates in patients with obstructed breathing

Christian HallerCEO

Crediwatch

Crediwatch

Bangalore, India

www.crediwatch.com

Credit intelligence, financial insights, and tools to empower lenders and businesses

Meghna SuryakumarCEO

DASI Simulations

DASI Simulations

Dublin, OH

dasisim.ai

Personalized medicine using simulation to transform the safety of care for structural heart disease patients

Teri Sirset, MSCEO

Deep Blue Medical Advances, Inc.

Deep Blue Medical Advances, Inc.

Durham, NC

www.deepbluemedical.com

Novel hernia mesh solution

Bill PerryCEO

Discure Medical

Discure Medical

Herzlyia, Israel

www.rainbowmd.com

Minimally invasive implant to reverse spinal disc degeneration

Yuval MandelbaumCEO

EarthGrid

EarthGrid

Richmond, CA

www.earthgrid.io

Plasma tunnel-boring robot, 100X faster with lower cost

Troy HelmingCEO

EchoPixel

EchoPixel, Inc.

Santa Clara, CA

echopixeltech.com

Real-time 4D holographic digital twin of a patient’s heart

Sergio AguirreCEO

Enduralock

Enduralock

Lenexa, KS

www.enduralock.com

Vibration resistant fasteners for aerospace and oil & gas

Dr. Harold HessCEO

Epilogue Systems

Epilogue Systems

Villanova, PA

www.epiloguesystems.com

Create in-app guidance and training resources for accelerated adoption of enterprise software

Mike GrahamCEO

EuMentis Therapeutics Inc.

EuMentis Therapeutics Inc.

Boston, MA

http://eumentistx.com

Novel therapeutics for treating neurodevelopmental and neurodegenerative diseases

Mark Tepper, PhDCEO

Everykey Inc

Everykey Inc

Cleveland, OH

https://everykey.com

Bluetooth key replacement device for phone, laptop, house, and car

Chris WentzCEO

Exodos Life Sciences Partners

Exodos Life Sciences Partners

Chapel Hill, NC

www.exodosls.com

Incubator funds promising biotech research & spins out

Wade FickenCEO

FemtoDx, Inc.

FemtoDx, Inc.

Los Angeles, CA

www.femtodiagnostics.com

Doctor’s office blood tests for cancer

Raj Mohanty, PhDCEO

FluidAI Medical

FluidAI Medical

Kitchener, ON, Canada

fluidai.md

Real-time monitoring for anastomotic leaks

Youssef HelwaCEO

Green Sun Medical

Green Sun Medical

Fort Collins, CO

www.greensunmedical.com

Dynamic spinal alignment brace for scoliosis

Jamie HaggardCEO

Healionics

Healionics

Seattle, WA

https://healionics.com

Artificial blood vessel for dialysis greatly reducing occlusions and infection

Mike ConnollyCEO

iDentical, Inc.

iDentical, Inc.

Mountain View, CA

www.identicalimplant.com

Personalized, drill-free dental implants modeled from the patient’s own tooth

Iris Wedeking, MBACEO

i-Lumen Scientific, Inc.

i-Lumen Scientific, Inc.

Bloomington, MN

www.i-lumenscientific.com

Non-invasive pulsed microcurrent stimulation to treat dry AMD

John VeLureCEO

inBay Technologies Inc.

inBay Technologies Inc.

Ottawa, Ontario, Canada

www.inbaytech.com

Enterprise authentication technology that cannot be hacked

Shane YoungCEO

infiniDome

infiniDome

Caesarea, Israel

www.infinidome.com

End-to-end GPS protection from jamming attacks

Omer ShararCEO

Inhalon Biopharma Inc.

Inhalon Biopharma Inc.

Chapel Hill, NC

www.inhalon.com

Monoclonal antibodies for the treatment and prevention of respiratory infections

John WhelanCEO

InterShunt Technologies, Inc.

InterShunt Technologies, Inc.

Plymouth, MN

https://intershunt.com

Interatrial shunting device that requires no implant and no energy, for the treatment of heart failure

Harlee SorkinCEO

IRIS R&D Group Inc.

IRIS R&D Group Inc.

Burlington, ON, Canada

www.irisradgroup.com

End-to-end data collection and reporting for smart cities and automated road monitoring

Emil RamosCEO

KalGene Pharmaceuticals

KalGene Pharmaceuticals

Montreal, QC, Canada

www.kalgene.com

Alzheimer’s disease lead molecule with no ARIA risk and superior biological efficacy

Nickolay Kukekov, PhDCEO

Kiana Analytics, Inc.

Kiana Analytics, Inc.

Sunnyvale, CA

https://kiana.io

Device detection & location-based analytics to automate site management, physical security, & digital contact tracing

Nader FathiCEO

KitoTech Medical

KitoTech Medical

Seattle, WA

www.kitotechmedical.com

Wound closure devices to replace stitches

Ronald Berenson, MDCEO

KuantSol

KuantSol

Palo Alto, CA

kuantsol.ai

Simplifying the process of predictive modeling

Aytekin OldacCEO

Lifewave Biomedical, Inc.

Lifewave Biomedical, Inc.

Los Altos, CA

lifewavebiomedical.com

Non-invasive lung sensor improving the clinical management of patients with CHF

Steve StephansenCEO

Life Detection Technologies, Inc.

Life Detection Technologies, Inc.

Sunnyvale, CA

lifedetectiontechnologies.com

Contactless device captures overnight heart and respiration rates for remote care of chronically ill patients

Eric HowieCEO

Light Line Medical, Inc.

Light Line Medical, Inc.

Salt Lake City, UT

www.lightlinemedical.com

Proprietary visible-light method for preventing and treating infections

Vicki Farrar, JDCEO

Loliware Inc.

Loliware Inc.

San Francisco, CA

www.loliware.com

World’s first seaweed pellet that can be processed on existing plastic equipment

Sea BrigantiCEO

ACQUIRED BY ACELRX
Lowell Therapeutics, Inc.

Lowell Therapeutics, Inc.

Lowell, MA

Anticoagulant for dialysis patients

James WilkieCEO

Madorra

Madorra

Portland, OR

www.madorra.com

Medical device that restores vaginal vibrancy without hormones

Holly RockweilerCEO

Makani Science

Makani Science

Irvine, CA

makaniscience.com

Wearable patch sensor that continuously monitors breathing

Greg Buchert, MDCEO

Marel Power Solutions, Inc.

Marel Power Solutions, Inc.

Saline, MI

marel-power.com

Miniaturized and scalable high-density power stack platform for inverters

Amrit VivekanandCEO

Micronic Technologies, Inc.

Micronic Technologies, Inc.

Bristol, VA

www.micronictechnologies.com

Industrial wastewater purification technology approaching 100% water reuse

Karen D. SorberCEO

Mitre Medical

Mitre Medical

Morgan Hill, CA

www.mitremedical.com

Medical heart device requiring no chest opening for insertion

John MacMahonCEO

mmTron Inc.

mmTron Inc.

Belmont, CA

mmtron.com

5G mmwave ultra-linear power-efficient broadband products

Seyed Tabatabaei, PhDCEO

Nanochon, LLC

Nanochon, LLC

Burke, VA

www.nanochon.com

3D printed implants to replace lost or damaged cartilage

Benjamin HolmesCEO

Navaux, Inc.

Navaux, Inc.

Little Rock, AR

www.navaux.com

Quantifying circulating levels of Hepsin in the blood for early cancer detection

Don E. FowlerCEO

Neuro42

Neuro42

Oakland, CA

http://neuro42.ai

Portable MRI for neuro imaging and interventions

Amit Vohra, PhD, MBACEO

NeuroFlow

NeuroFlow

Philadelphia, PA

www.neuroflowsolution.com

Software for hospitals to ensure mental patient compliance with programs

Christopher MolaroCEO

New View Surgical

New View Surgical, Inc.

Boston, MA

http://newviewsurg.com

Visualization of the surgical field directly through each access port

Bryce KlontzCEO

NuvOx Pharma

NuvOx Pharma

Tucson, AZ

https://www.nuvoxpharma.com/

First-in-class oxygen therapeutic to treat life-threatening diseases where hypoxia plays a role

Evan Unger, MDCEO

Octagon Therapeutics

Octagon Therapeutics

Cambridge, MA

www.octagontherapeutics.com

Targeted inhibition of diseased immune cells while sparing beneficial immune functioning

Isaac StonerCEO

Orion Biotechnology Canada, Ltd.

Orion Biotechnology Canada, Ltd.

Ottawa, Canada

https://orionbiotechnology.com

Novel chemokine analogs for oncology, neuroinflammation, and infectious disease treatments

Mark GroperCEO

Otomagnetics, Inc

Otomagnetics, Inc

Rockville, MD

http://otomagnetics.com

Non-invasive magnetically assisted drug delivery to ears, eyes, and skin

Abhita BatraCEO

Patheous Health, Inc.

Patheous Health, Inc.

Leawood, KS

www.patheous.health

Mobile dysphagia diagnostics to improve the assessment and treatment of swallowing impairment

Michael PeckCEO

Perceptive

Perceptive Technologies, Inc.

Formerly “Cyberdontics”

Boston, MA

www.perceptive.io

Painless automated laser-based crown surgery

Chris Ciriello, DDSCEO

Perikinetics, Inc.

Perikinetics, Inc.

San Francisco, CA

http://pkhealth.co

True “set it and forget it” artificial pancreas for diabetes management

Christopher HansonCEO

Polymertal Ltd.

Polymertal Ltd.

Haifa, Israel

polymertal.com

New breed of metal-infused polymers

Ran CarmeliCEO

PreView Medical, Inc

PreView Medical, Inc

Longmont, CO

www.previewmedical.com

Smarter biopsy needle with integrated optics for real-time spectroscopy during a prostate biopsy

Amir TehraniCEO

Promaxo

Promaxo

Oakland, CA

http://promaxo.com

Low-Cost MRI Machines for early cancer detection

Amit Vohra, PhD, MBACEO

Rapid Nexus

Rapid Nexus

Irvine, CA

rapidnexus.com

Nanotechnology wound treatment system for chronic and nonhealing wounds

Dr. Margaret KalmetaCEO

Raydiant Oximetry

Raydiant Oximetry

San Ramon, CA

www.raydiantoximetry.com

Non-invasive fetal oximeter to keep mothers & babies safe during childbirth

Neil Ray, MDCEO

Response Pharmaceuticals

Response Pharmaceuticals

McLean, VA

responsepharmaceuticals.com

Developing first-in-class iMTP inhibitor for treating the metabolic side effects of antipsychotic drugs

Eric Keller, JDCEO

Rhaeos, Inc.

Rhaeos, Inc.

Evanston, IL

www.rhaeos.com

Wearable wireless skin sensors that can assess flow throughout the body

Anna Lisa Somera, MBACEO

RiSo Capital

RiSo Capital

Saratoga, CA

https://risocapital.com

Seed investor for India based tech startups

Sri PurisaiCEO

Saccharo, Inc.

Saccharo, Inc.

Oakland, CA

www.saccharo.com

Proprietary mAbs against a novel cancer target

Sherry Martin-Moe, PhDCEO

SageMedic, Corp.

SageMedic, Corp.

Redwood City, CA

www.sagemedic.com

Direct testing of dozens of therapies upon 3D micro-tumors

Chris Apfel, MD, PhD, MBACEO

Sanolla

Sanolla

Nesher, Israel

sanolla.com

Smart infrasound-based diagnostics solutions for physicians and patient self-assessment

Doron Adler, PhDCEO

Seal Rock Therapeutics, Inc.

Seal Rock Therapeutics, Inc.

Seattle, WA

www.sealrocktx.com

Focused on NASH fatty liver opportunities

Neil McDonnell, PharmDCEO

Single Pass Inc.

Single Pass Inc.

Lake Forest, CA

singlepass.co

Patented disposable bipolar electrocautery device

Bill ColoneCEO

Spintly

Spintly

Milpitas, CA

spintly.com

Smart access control that replaces badges, fobs, and keys with your smartphone

Rohin ParkarCEO

TibaRay

TibaRay

Fremont, CA

tibaray.com

Ultra-efficient linear accelerator to power ultra-rapid cancer radiotherapy

Peter Schwartz, PhDCEO

Trellis Bioscience

Trellis Bioscience

Redwood City, CA

http://trellisbio.com

Fighting antibiotic resistance with human-derived rare and optimized antibodies

Stefan Ryser, PhDCEO

Trio Labs

Trio Labs

Morrisville, NC

www.trio-labs.com

Proprietary 3D printing technology for precise micro metal components

Adam SteegeCEO

Valfix

Valfix

Tel-Aviv, Israel

www.valfixmed.com

Trans-catheter solution offering a viable alternative to open heart surgery

Eli BarCEO

VESTECK Inc.

VESTECK Inc.

West Chester, PA

vesteck.com

“Suture-Tight” catheters that secure endovascular aortic repair grafts to the aorta

Joseph RaffertyCEO

Visgenx, Inc.

Visgenx, Inc.

San Diego, CA

https://visgenx.com

Therapeutics for Age-related Macular Degeneration (AMD)

William PedrantiCEO

Xpan Inc.

Xpan Inc.

Toronto, Canada

http://xpanmedical.com

Next-gen expandable trocars for minimally invasive surgical access

Zaid AttoCEO